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Bone Graft
Osteon III is a synthetic osteoconductive bone graft material with excellent wettability, easy manipulation and a highly interconnected porous structure (micro- and macro-pores, approx. 80% porosity) facilitating new bone formation. Osteon III, as a synthetic bone graft material, eliminates any risk of disease transmission. Its composition makes it suitable for applications where bone grafting is desired for long term volume maintenance, such as ridge augmentation, sinus lift, cystic cavities, etc., due to its high content of HA (60%)
100% synthetic bone graft material: HA (60%) + β-TCP (40%)
Applications• Periodontal Defect
• Ridge Augmentation
• Extraction Site
• Cystic Cavities
• Sinus Lift
1.Sinus
2.Lift
• Space maintenance
• Easy handling
• Excellent wettability
• Osteoconductive synthetic bone graft
• Pore Size : 200~400㎛
• Porosity: 80%
• Periodontal defect
• Ridge augmentation
• Extraction site
• Cystic cavities
• Sinus Lift & Osteotomy
Features• High connection porosity and specific surface area
• Connectivity between macropore and micropore optimization (Porosity: more than 80%)
• Excellent agglomeration between bone graft materials
Instruction for OSTEON 3 Sinus & Lifting
Simultaneous lateral bone augmentation and implant placement using a particulated synthetic bone substitute around chronic peri-implant dehiscence defects in dogs
Ui-Won Jung, Jae-Kook Cha, Fabio Vignoletti, Javier Nuñez, Javier Sanz, Mariano Sanz
(J Clin Periodontol. 2017 Nov;44(11):1172-1180. doi: 10.1111/jcpe.12802. Epub 2017 Sep 21)
A Comparative Study with Biphasic Calcium Phosphate to Deproteinized Bovine Bone in Maxillary Sinus Augmentation: A Prospective Randomized and Controlled Clinical Trial
Ji-Su Oh, Yo-Seob Seo, Gyeong-Je Lee, Jae-Seek You, Su-Gwan Kim
(Int J Oral Maxillofac Implants. January/February 2019;34(1):233–242. doi: 10.11607/jomi.7116. Epub 2018 Dec 5)
Comparison of Three Biphasic Calcium Phosphate Block Substitutes: A Histologic and Histomorphometric Analysis in the Dog Mandible
Octavi Ortiz-Puigpelat, Basel Elnayef, Marta Satorres-Nieto, Jordi Gargallo-Albiol, Federico Hernández-Alfaro
(Int J Periodontics Restorative Dent. May/Jun 2019;39(3):315-323. doi: 10.11607/prd.3837)
Evaluation of different combinations of Biphasic calcium phosphate and growth factors for bone formation in calvarial defects in a rabbit model
Sung-Min Chung, In Kwon Jung, Byung-Ho Yoon, Bok Ryul Choi, David M Kim, Jung Sun Jang
(Int J Periodontics Restorative Dent. 2016;36 Suppl:s49-59. doi: 10.11607/prd.2633.)
The clinical and radiographic outcomes of Schneiderian membrane perforation without repair in sinus elevation surgery
Won-Bae Park, Ji-Young Han, Philip Kang, Fatemeh Momen-Heravi
(Clin Implant Dent Relat Res. 2019 Oct;21(5):931-937. doi: 10.1111/cid.12752. Epub 2019 Apr 4.)
Bone Graft
Osteon II is a synthetic osteoconductive bone graft material with higher content of β-TCP compared to Osteon III. It possesses interconnected porous (micro and macro-pores, approx. 70% porosity) structure similar to that of cancellous bone. Osteon II as, a synthetic bone graft material eliminates any risk of disease transmission. Its composition makes it suitable where new bone formation is desired, such as extraction socket preservation, periodontal defects, and etc., due to its high content of β-TCP (70%)
100% synthetic bone graft material: HA (30%) + β-TCP (70%)
Applications• Alveolar bone augmentation
• Filling of lost areas around implants
• Filling of tooth extraction area to protect alveolar bone
• Maxillary sinus lift surgery
• Filling of Periodontal defects
1.Sinus
2.Lift
• Highly resorbable due to higher β-TCP content
• Easy handling
• Excellent wettability
• Osteoconductive synthetic bone graft
• Pore Size : 250㎛
• Porosity : 70%
• Extraction site grafting
• Ridge augmentation
• Cystic cavities
• Sinus lift & osteotomy
• Periodontal defect
Characteristic:• Osteoconductive synthetic bone graft material
• Pore size: approximately 250㎛ (Micro CT measurement)
• Porosity: more than 70%
Instruction for OSTEON II Sinus & Lifting
Alveolar ridge reconstruction with a composite alloplastic biomaterial
David M Kim, Marcelo Camelo, Myron Nevins, Ardavan Fateh, Peter Schupbach, Marc Nevins
(Int J Periodontics Restorative Dent. 2012 Dec;32(6):e204-9)
Ridge Preservation With and Without Primary Wound Closure: A Case Series
David M Kim, Nicola De Angelis, Marcelo Camelo, Marc L Nevins, Peter Schupbach, Myron Nevins
(Int J Periodontics Restorative Dent. Jan-Feb 2013;33(1):71-8. doi: 10.11607/prd.1463)
The Clinical and Histologic Outcome of Dental Implant in Large Ridge Defect Regenerated With Alloplast: A Randomized Controlled Preclinical Trial
David M Kim, Marc L Nevins, Zhao Lin, Ardavan Fateh, Soo-Woo Kim, Peter Schupbach, Myron Nevins
(J Oral Implantol. 2013 Apr;39(2):148-53. doi: 10.1563/AAID-JOI-D-12-00242)
A Prospective, Randomized Controlled Preclinical Trial to Evaluate Different Formulations of Biphasic Calcium Phosphate in Combination With a Hydroxyapatite Collagen Membrane to Reconstruct Deficient Alveolar Ridges
David M Kim, Marc L Nevins, Zhao Lin, Ardavan Fateh, Soo-Woo Kim, Peter Schupbach, Myron Nevins
(J Oral Implantol. 2013 Apr;39(2):148-53. doi: 10.1563/AAID-JOI-D-12-00242)
Effect of different hydroxyapatite:β-Tricalcium Phosphate ratios on the osteoconductivity of Diphasic Calcium Phosphate in the rabbit sinus model
Hyun-Chang Lim, Ming-Lan Zhang, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi
(Int J Oral Maxillofac Implants. Jan-Feb 2015;30(1):65-72. doi: 10.11607/jomi.3709. Epub 2014 Sep 26)
Biphasic hydroxyapatite and β-tricalcium phosphate biomaterial behavior in a case series of maxillary sinus augmentation in humans
Allinson Olaechea, Gerardo Mendoza-Azpur, Francisco O Valle, Miguel Padial-Molina, Natividad Martin-Morales, Pablo Galindo-Moreno
(Clin Oral Implants Res. 2019 Apr;30(4):336-343. doi: 10.1111/clr.13419. Epub 2019 Mar 24)
Regeneration Membrane
Dentium Collagen Membrane is a resorbable and multi-layered thin barrier membrane designed for a guided bone/tissue regeneration procedure. It is made by crosslinking of pure collagen type I derived from bovine tendon. It features:
• Absorbable membrane composed of bovine-derived highly pure type I collagen
• Absorbent membrane that degrades after stable lasting for 6 months
• Dual sided use
Biodegradable barrier membrane for guided bone / tissue regeneration
Applications• Periodontal / Intra-bony Defect
• Ridge Augmentation
• Extraction Socket Grating
• Guided Bone Regeneration Sinus Lift
• Pure Type 1 Collagen derived from New Zealand bovine tendon.
• Thin membrane (300µm) with multiple layers for easy manipulation and good mechanical strength in surgery.
• Resorption period provides enough time for stabilizing graft materials and supporting bone growth.
• Dual-sided usage.
• Periodontal / Intrabony Defects.
• Ridge Augmentation.
• Extraction Socket Grafting.
• Guided Bone Regeneration (GBR).
• Sinus lift
Features:• A 300㎛ thin membrane with a multi-layer thin film structure provides sufficient physical properties during surgery.
• The absorption period is 6 months, providing sufficient time for stabilization of the transplant site and production of the new bone.
• The multi-layered thin film structure facilitates the proliferation of osteoblasts and provides sufficient space for the formation of new bone.
Animal Test ResultRabit Calvaria Model, 6~12 weeks (Masson Trichrome)
Physicochemical characterization of barrier membranes for bone regeneration
Jordi Caballé-Serrano, Antonio Munar-Frau, Luis Delgado, Roman Pérez, Federico Hernández-Alfaro
(J Mech Behav Biomed Mater. 2019 Sep;97:13-20.
doi: 10.1016/j.jmbbm.2019.04.053. Epub 2019 May 4.)
A Comparative Study with Biphasic Calcium Phosphate to Deproteinized Bovine Bone in Maxillary Sinus Augmentation: A Prospective Randomized and Controlled Clinical Trial
Ji-Su Oh, Yo-Seob Seo, Gyeong-Je Lee, Jae-Seek You, Su-Gwan Kim
(Int J Oral Maxillofac Implants. January/February 2019;34(1):233–242. doi: 10.11607/jomi.7116. Epub 2018 Dec 5)
Comparison of Three Biphasic Calcium Phosphate Block Substitutes: A Histologic and Histomorphometric Analysis in the Dog Mandible
Octavi Ortiz-Puigpelat, Basel Elnayef, Marta Satorres-Nieto, Jordi Gargallo-Albiol, Federico Hernández-Alfaro
(Int J Periodontics Restorative Dent. May/Jun 2019;39(3):315-323. doi: 10.11607/prd.3837)
